40S Ribosomal Subunits

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Bacterial Chemotherapy Part 1 Blocking of Antibiotic Transport Inactivation of Antibiotics OR Enzymatic Detoxification Bypass Mechanisms Inhibition of Protein Synthesis Stages of Translation in Protein Synthesis Initiation Process in Translation in Protein Synthesis Elongation Process in Translation in Protein Synthesis Termination Process in Translation in Protein Synthesis

30S/40S Ribosomal Subunits

	30S/-40S Ribosomal Subunits - The aminoglycoside aminocyclitol antibiotics contain both an amino sugar and an aminocyclitol (with the exception of spectionomycin). They are divided into two classes. Class I - Those containing streptidine, e. g. streptomycin and derivatives. Class II - Those containing deoxystreptamine.
1. Substituents attached to 4-and 5-hydroxyls of deoxystreptamine. e.g. neomycin, ribostamycin and paromomycin. 2. Substituents attached to 4-and 6-hydroxyls of deoxystreptamine e.g. kanamycins, gentamycins and tobramycins.

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Bacterial Chemotherapy Part 1 Supernatant Folic Acid Antagonists Aminoalkyl Adenylates Diptheria Toxin 30S/40S Ribosomal Subunits Aminoglycosides Streptomycin Neomycin, Kanamycin and Gentamycin Tetracycines Edeine 50S/60S Ribosomal Subunit Chloramphenicol Macrolides Lincosamides Puromycin Sparsomycin Glutarimides Cycloheximide Ipeal Alkaloids Emetine