Microbiology Procedure
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Antibiotics Affecting The Cell Wall Peptidoglycan Biosynthesis

Antibiotics Affecting The Cell Wall Peptidoglycan Biosynthesis - One important difference between bacterial and animal cells is that the former have a cell wall. Thus any antibiotic which acts selectively against the cell wall would be able to control bacterial multiplication. Gram positive bacteria have a relatively simple cell envelope consisting of a cell membrane, outside which is the actual cell wall consisting of two main layers, the peptidoglycan layer and the teichoic acid layer (teichuronic acid in some bacteria).

In gram negative bacteria the cell envelope consists of two membranes, an outer cell wall and an inner cytoplasmic membrane, with a thin peptidoglycan layer in between. An outline of the biosynthesis of peptidoglycan in Staphylococcus aureus.

 

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