Diptheria Toxin

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Bacterial Chemotherapy Part 1 Blocking of Antibiotic Transport Inactivation of Antibiotics OR Enzymatic Detoxification Bypass Mechanisms Inhibition of Protein Synthesis Stages of Translation in Protein Synthesis Initiation Process in Translation in Protein Synthesis Elongation Process in Translation in Protein Synthesis Termination Process in Translation in Protein Synthesis

Diptheria Toxin

Diptheria Toxin - The intact diphtheria toxin (MW-63,000) is enzymatically inactive. After attachment to the cell it enters the cytosol and is cleaved into two fragments, A (MW 24,000) and B (MW 39,000). Fragment B is necessary for the attachment of the toxin to the cell. Fragment A inactivates the free form of EF-12.

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Bacterial Chemotherapy Part 1 Supernatant Folic Acid Antagonists Aminoalkyl Adenylates Diptheria Toxin 30S/40S Ribosomal Subunits Aminoglycosides Streptomycin Neomycin, Kanamycin and Gentamycin Tetracycines Edeine 50S/60S Ribosomal Subunit Chloramphenicol Macrolides Lincosamides Puromycin Sparsomycin Glutarimides Cycloheximide Ipeal Alkaloids Emetine

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