Vancomycin And Ristocetein -These drugs must be administered intravenously, and have side effects. They, therefore, have limited application in medicine, and are used only in severe infections resistant to other antibacterial agents. They appear to inhibit peptidoglycan synthesis at a later stage than oxamycin. Sub-inhibiting concentrations cause accumulation of, precursors, including the nucleotide pentapeptide.
