Assimilation And Asymmetric Strand Transfer

Assimilation And Asymmetric Strand Transfer

Assimilation And Asymmetric Strand Transfer -According to one concept, strand transfer takes place by displacement plus assimilation. Displacement is promoted by new synthesis. Assimilation is promoted by exonucleases that act either on ssDNA or dsDNA. DNA polymerase I of E. coli promotes all the requisite functions, i. e. synthesis, displacement of strand and 5'3' exonucleo lytic digesion.

Another possible mechanism for the incorporation of a single strand into the helix is by the enzyme gyrase, which appears to promote extensive strand uptake of a single strand by increasing the free energy of the superhelix

Broker and Lehman (1971) used the terms I single strand branch migration and double strand branch migration to describe exchange of strands in structures like those (a) and (b) respectively.

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