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Index >> Bacterial Structure >> Peptidoglycans,Mucopeptides, Glycopeptides, Mureins

Peptidoglycans,Mucopeptides,Glycopeptides,Mureins

Peptidoglycans,Mucopeptides,Glycopeptides,Mureins

- Peptidoglycans (mucopeptides, glycopeptides, mureins) are the structural elements of all most all bacterial cell walls.

Halobacterium and Halococcus are the only prokaryotes known which do not have peptidoglycan in their cell walls.

This is because these organisms live in environments of high salt concentrations, and their cell contents are isosmotic with the environment.

A strong cell wall is therefore unnecessary.

The cell walls of gram negative bacteria have a comparatively, low peptidoglycan content (5-10% of the weight of the wall).

There is a low degree of cross linkage between the glycan strands of peptido­glycan.

In many gram negative bacteria the peptidoglycan layer is a monolayer, or, at the most, a bilayer.

In E. coli, peptidoglycan consists of linear polysaccharide chains consisting of alternating residues of the amino sugars N-acetyl glucosamine (NAG) and N-acetyl muramic acid (NAM) linked by β-1-4-glycosidic bonds.

Free tetrapeptide side chains are attached to the NAM residues.

Some adjacent NAM residues are directly cross-linked by tetrapeptide side chains.

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