Lysogenic
Cycle -
The two characteristic features of lysogenic bacteria are immunity and induction. The prophage, which is incorporated into the bacterial I genome, may be inherited just like any bacterial gene, any maybe carried indefinitely in the inert condition.
The presence of the prophage confers immunity on the bacterial cell against superinfection.
Lysogenic
cells are not infected by other lambda phage particles and therefore do not undergo lytic bacterial infection.
The prophage can, however be induced under certain conditions to enter the lytic cycle. Induction may occur spontaneously, or may be stimulated by UV irradiation or mitomycin C.essful.
The lysogenic state is brought about in two stages, establishment and maintenance.
Establishment of lysogeny requires the integration (insertion) of the phage genome into the bacterial chromosome and the beginning of repressor synthesis to prevent expression of genes bringing about lysis.
Establishment requires the participation of three control genes, cI, cII and cIII,. Maintenance of lysogeny only requires that repressor synthesis continue. This is brought about by the transcription and translation of a single gene, cI.
