The affinity of the DNA binding protein is much greater for denatured DNA than for dsDNA. The protein is therefore able to maintain ssDNA in that state. Its role appears to be to provide a single stranded template for DNA polymerase.
It has been found to stimulate DNA polymerase activity in vitro. The DNA binding protein maintains DNA in the single stranded state ahead of the replication fork. The DNA polymerase thus comes into contact with only single strands as it proceeds with replication
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