Microbiologyprocedure.com Community Toolbar Download ImageSubmit Your College, Institute, Company, Products for FREE
  Home  Link to us  DirectoryNEW  Site map  Search  Language

Index >> Cellular Components >> Amino Acids

Amino Acids

Amino Acids - The basic units in all proteins are amino acids and the number and sequence of these amino acids in a protein is what distinguishes one from the other. Each amino acid is different from the other in the R group or the side chain. Their common features include an (α-carbon atom, an α-carboxyl group, an α-amino group and a side chain attached to the α-carbon.

The carboxyl and the amino groups are involved in the peptide bond formation which serve as the connecting links between amino acid residues within the polypeptide chain. With the exception of glycine all the amino acids are asymmetric around the α-carbon namely L and D, distinguished by the direction in which each rotates the polarized light. Amino acids found in natural proteins are of L-configuration.

D-amino acids have been found in the cell walls of bacteria and in certain bacterial antibiotics such as gramicidin. For details of the chemistry of amino acids and their biosynthesis, the reader may refer to any standard work on biochemistry.

The carbon skeletons for the biosynthesis of amino acids are supplied by the break down of carbohydrates. An essential feature of amino acid biosynthesis is the introduction of nitrogen into the carbon skeleton and this is usually achieved by the addition of ammonia to the keto acid in the process known as amination. One simplest example of this is the conversion of pyruvate to alanine, shown below:

Home | Site map | Submit Article | Directory | Search