This
sequence
is
specific
for
a
particular
enzyme
and
determines
the
properties
of
the
enzyme.
The
amino
acid
sequence
and
the
three
dimensional
structure
Eave
been
determined
for
the
enzymes
egg
white
lysozyme,
ribonuclease,
carboxypeptidase,
chymotrypsin
and
papain.
Lysozyme hydrolyses links a between amino sugars, and is found in saliva and egg white. Ribonuclease degrades RNA into small fragments.
Chymotrypsin and trypsin are proteolytic enzymes found in the pancreas.
Chymotrypsinogen, the Inactive precursor of chymotrypsin, consists of a single polypeptide chain.
Removal of two dipeptides results in the active enzyme chymotrypsin, which consists of three polypeptide chains.
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