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Bacterial Food Intoxications

Bacterial Food Intoxications
A bacterial food intoxication refers to illness caused by the consumption of a bacterial toxin formed in the food, while a bacterial food infection refers to illness caused by the entrance of the bacteria into the body through ingestion of contaminated food and the reaction of the body to their presence or to their metabolites.

Infections in which food serves only as a carrier of the disease but does not allow the growth and multiplication of the pathogens, such as tuberculosis, typhoid fever, cholera etc., are different from those in which food serves as a culture medium for growth of the pathogens such as Salmonella, enteropathogenic E. coli, Bacillus, Clostridium etc.

There are two major food intoxications caused by the bacteria. These are: (i) botulism caused by the presence in food of toxin produced by Clostridium botulinum, and (ii) staphylococcal intoxication caused by the toxin produced by S. aureus.Botulism is an intoxication caused by the ingestion of food containing the neurotoxin (toxin that affects the nervous system) produced by anaerobic, spore forming Clostridium botulinum. There are seven types of toxins recognized on the basis of serological specificity . Toxin production by C. botulinum depends on the ability of the bacterial cells to grow in food and to autolyse. Therefore factors influencing spore germination, growth and toxin production such as the composition of the food, temperature of storage and pH are important. The main sources of botulism are canned meat, fish, string beans, sweet corn, beets and other low medium acid foods. Spores of C. botulinum survive long storage periods in raw and precooked frozen foods and can grow when conditions are ideal. The toxin of C. botulinum is a protein. It is absorbed mostly in the small intestine and paralyses the involuntary muscles. The heat treatment necessary to destroy this toxin depends on the type of toxin. For example, heat treatment at" 80°C for 5.6 minutes will inactivate type 'A' toxin  while type 'B' toxin can be inactivated only by heating at 90°C for 45 minutes.

Typical symptoms of botulism usually occur within 12-36 hours after consumption of the spoilt food. Early symptoms are digestive disturbances followed by nausea, vomitting, diarrhoea, together with dizziness and headache. Double vision may occur early and there may be difficulty in speaking. Mouth may become dry, throat constricted, tongue may get swollen and coated. Involuntary muscles become paralysed and paralysis spreads to the respiratory system and to the heart. Death normally results from respiratory failure. In fatal cases, death occurs within 3-6 days after the poisonous food has been ingested but the period may vary.

The methods of botulism prevention include: (i) the use of approved heat processes for canned foods, (ii) rejection of all spoilt canned foods, (iii) by avoiding food that has been cooked and not well heated, and (iv) boiling of suspected food for at least 15 minutes. The only known method of successful treatment of botulism is by the administration of antitoxin. This treatment may not be successful once the symptoms appear but may prove useful if administered in the very early stages.

A second and most common type of food intoxication is the staphylococcal food intoxication resulting from the ingestion of food contaminated with the enterotoxin produced by certain strains of S. aureus. The illness starts usually 2-6 hours after ingestion of the contaminated food and is manifested by the onset of nausea, vomitting, abdominal pain and diarrhoea. In severe cases, dehydration and collapse may occur. The symptoms can last upto 24 hours but recovery is rapid even from a state of collapse.

The stapylococcal enterotoxins are proteins with a molecular weight of 30-35,000 daItons and are composed of single polypeptide chains The toxins are resistant to proteolytic enzymes such as trypsin and renin. Moreover, the toxins are relatively beat stable and subsequent cooking may kill the staphylococci but the toxin may still remain. Although purified toxins may be inactivated by heat, they are much more heat resistant when they are in foods. Several distinct types of enterotoxins are produced by different strains of S. aureus which tan be identified with the help of specific antisera. At least five enterotoxins, A, B, C, D and E have been identified and implicated in food poisoning

Staphylococci are commonly found on the skin, nose and other parts of healthy people. They are usually transferred to the food through the hands of the handlers. If the contaminated food is stored at temperatures that encourage the growth of these organisms, production of enterotoxins may occur. It is important that all susceptible foods such as cold meat, poultry, cream cakes, cooked sea foods etc., are stored at low temperatures to prevent the growth of these bacteria.

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