Codon Changes and Amino Acid Replacements in Haemoglobins

Codon Changes and Amino Acid Replacements in Haemoglobins

Codon Changes and Amino Acid Replacements in Haemoglobins -

Amino acid in normal haemoglobin	Base Substitution	Amino acid in mutant haemoglobin
Lysine (AAA)	A-->G	Glutamic acid (GAA)
Glycine (GGU)	G-->A	Aspartic acid (GAU)
Asparagine(AAU)	U-->A	Lysine (AAA)
Glutamic acid (GAA)	A-->U	Valine (GUA)

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Suppressor Genes Frameshift Suppressions Molecular Basis of Mutations Spontaneous Mutations Tautomerism Induced Mutations Chemical Mutagens Base Analogues Agents Modifying Purines and Pyrimidines OR Agents Labilize the Bases Agents Producing Distortions in DNA Radiations Types of Mutations