Thus if the message given below is read
from left to right the first codon, UUG, would specify leucine.
If read Codons UUG AUC GUC UCG CCA ACA AGG --> Leu Ile Val Ser Pro Thr Arg Val Leu Leu Ala Thr Thr Gly <-- from
right
to
left
the
codon
would
become
GUU
and
would
specify
valine.
It
is
thus
seen
that
the
sequence
of
amino
acids
constituting
the
protein
would
undergo
a
drastic
change
if
the
code
is
read
in
the
opposite
direction.
The available evidence indicates that the message in mRNA is read in the 5'-->3' direction.
The polypeptide chain is synthesized in the N-->C direction, i.e. from the amino (NH2) terminal to the carboxyl (COOH) terminal.
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