Index >> Chromosomal Aberrations >> Genetic Significance of Heterozygotic Translocation

Genetic Significance of Heterozygotic Translocation
1. The heterozygous translocation produce semi-sterile organisms because between half and two third gametes fail to receive the full complements of genes required for normal development of sex.
2. Some genes which formerly assorted independently, exhibit linkage relationships after translocation has occurred; a single reciprocal translocation will reduce the number of linkage groups by one.
3. The phenotypic expression of a gene may be modified when it is translocated to a new position in the genome (position effect).
Induction of Chromosomal Aberrations
Most chromosomal aberrations are caused due to the accidental, natural or induced breakage of chromosomes. The induced chromosomal breakage may be casued by radiations and chimicals such as Lysergic acid diethylamide (LSD) (Lisco and Conard, 1967; Irwin and Egozcue. 1967).