Microbiologyprocedure.com Community Toolbar Download ImageSubmit Your College, Institute, Company, Products for FREE
  Home  Link to us  DirectoryNEW  Site map  Search  Language

Index >> Chromosomal Aberrations >> Interchromosomal Aberrations

Interchromosomal Aberrations

Interchromosomal Aberrations
When breaks occur in non-homologous chromosomes and resulting fragments are interchanged by both of the non-homologous chromosomes, the inter-chromosomal or heterosomal aberrations occur. The inter-chromosomal aberration is of following type:
Translocation
Translocation involves the shifting of a part of one chromosome to another non-homologous chromosome. If two non-homologous chromosomes exchange parts, which need not be of the same size, the result is a reciprocal translocation. The reciprocal translocation may be of following types :
1. Homozygotic translocation-In homozygotic translocation normal meiosis occur and cannot be detetced cytologically. Genetically they are marked by altered linkage group by the fact that a gene with new neighbours may produce a somewhat different effect in its new location (position effect).

Homozygotic and heterozygotic translocation

Normal
Homozygotic translocation
Heterozygotic translocation


(ii) Heterozygotic translocation-In heterozygotic translocation a considerable degree of meiotic irregularity occur. During meiosis, an individual which is heterozygous for a reciprocal tranrlocation must form a cross-shaped configuration in order to affect pairing of all homologous segments. This cross-shaped configuration often opens out into a ring as chiasmata terminalize. The meiotic products (gametes) are of three types-normal balanced and unbalanced gametes as have been illustrated in following diagram:

Meiosis in heterozygotic translocation

1.Translocation 2.Meiosis
3.Normal diploid 4.Balanced translocation diploid
5.Synapsis 6.Unbalanced gametes
7.Normal gamete 8.Balanced translocation gamete
Home | Site map | Submit Article | Directory | Search