Index >> Chromosomal Aberrations >> Types of Inversions

(ii) Paracentric inversions- When the inverted segment includes no centromere and the centromere remains located outside the segment, then such type of inversion is called homobranchial or paracentric inversion. Crossing over within the inverted segment of a paracentric inversion, produces a dicentric and an acentric chromosome. The dicentric chromosome contains two centromeres and forms a bridge -from one pole to the other during first meiotic: anaphase. When anaphase chromosomes separate towards poles, this bridge breaks somewhere its length and the resulting fragments contain duplications and/or deficiencies. The acentric chromosome because lacks in centromere and fails to move to either pole and so, is not included in the meiotic products.