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Difference between Dominance and Epistasis
The phenomenon of dominance involves intra-genic or inter-allelic gene suppression, or the masking effect which one allele has upon the expression of another allele at the same locus, while the phenomenon of epistasis involves inter-genic suppression or the masking effect which one gene locus has upon the expression of another. The classical phenotypic ratio of 9 : 3 : 3 : I observed in the progeny of dihybrid parents becomes modified by epistasis into ratios which are various combinations of the 9 : 3 : 3 : 1 groupings