RNA Polymerase from Eukaryotes
The nuclei of different eukaryotes are found to contain three different types of RNA polymerase, called I, II, and III RNA polymerases. RNA polymerase I is belived to be localized exclusively in the nucleolus and involved in the synthesis of ribosomal RNA. Polymerase II and III are found outside the nucleolus and carry out the rest of nuclear transcription. All three enzymes have molecular weight greater than 500,000 and are presumed to be composed of subunits, but their molecular structures are not known like the prokaryotic enzymes (see Goodenough and Levine, 1974).





