Microbiologyprocedure.com Community Toolbar Download ImageSubmit Your College, Institute, Company, Products for FREE
  Home  Link to us  DirectoryNEW  Site map  Search  Language

Index >> Phenotypic Ratio >> Pleiotropism

Pleiotropism

Pleiotropism
Uptill now we have observed that a specific gene has a specific effect upon a specific phenotypic trait or in other words, each gene (allele) has its relation with a single phenotypic trait, but, this is not the case. A single gene often influences more than one phenotypic trait. However, it may be that one gene may cause evidently well marked expression of some phenotypic trait (major effect) than the others with less evident phenotype (secondary effect). Most genes have their multiple effects and are called pleiotropic genes. The phenomenon of multiple effect (multiple phenotypic expressions) of a single gene is called pleiotropism.
Examples of Pleiotropism
1. In Drosophila the recessive gene for vestigial wings cause vestigial wings in homozygous condition. However, careful observation show that other traits well are affected-(i) the tiny wing like balancer behind the wings; (ii) certain bristles; (iii) the structure of the reproductive organs; (iv) egg production is lowered, and, (v) longevity is reduced.

2. In human, the gene for disease phenylketonuria has pleiotropic effect and produces various abnormal phenotypic traits, collectively called syndrome. For example, the affected individuals secrete excessive quantity of amino acid phenylalanine in their urine, cerebrospinal fluid and blood. They become short stature, mentally deficient, with widely spaced incisors, with pigmented patches on skin, with excessive sweating and with non-pigmented hairs and eyes.

Home | Site map | Submit Article | Directory | Search