Fed
Batch
Culture -
Although
batch
and
continuous
culture
are
used
most
frequently
in
the
laboratory
and
are
most
useful
for
experimental
work,
industrial
processes
often
use
a
hybrid
of
the
two
techniques
called fed
batch
culture.
This
involves
ordinary
batch
growth
until
the
substrate
is
fully
utilised,
followed
by
regular
additions
of
fresh
substrate
which
is
then
rapidly
metabolised.
The
total
culture
volume
may
be
allowed
to
increase
or
portions
may
be
removed
as
fresh
substrate
is
added.
This
type
of
culture
was
developed
empirically
but
microbiologists
are
now
initiating
to
understand
the
physiology
of
growth
under
such
conditions
and
the
reasons
for
its
efficiency
in
terms
of
product
formation,
yield
and
greater
control.
This
may
lead
to
further
advances
in
industrial
microbiology
