Atopic
Diseases/Common
Allergy
The
above
mentioned
Type
I
hypersensitivity
need
not
result
in
the
whole
body
involvement
that
accompanies
anaphylaxis.
Indeed
the
vast
majority
of
hypersensitivity
reactions
are
accompanied
by
limited
production
of
IgE
and
the
sensitization
of
mast
cells
in
localised
areas
of
the
body.
The
result
is
an
atopic
disease,
or
common
allergy.
An
example
of
atopic
disease
is
hay
fever.
This
condition
results
from
inhalation
of
tree
and
grass
and
weed
pollens
in
particular
seasons
of
the
year.
Inmnune
stimulation
by
pollen
antigens
leads
to
IgE
production,
and
a
sensitization
of
mast
cells
follows
in
eyes,
nose
and
upper
respiratory
tract.
Subsequent
exposures
bring
sneezing,
tearing,
swollen
mucous
membranes
and
other
symptoms.





