Bruton's
Agammaglobulinemia
This
was
first
described
by
O.C
Bruton
in
1952.
Here
B Lymphocytes
fail
to
develop
from
pre
B
Lymphocyte
cells
in
the
bone
marrow.
The
lymphoid
tissues
lack
plasma
cells,levels
of
all
five
types
of
antibodies
are
low
or
absent
in
the
patient.
and
there
are
no
antibody
responses.
This
is
sex
linked
inherited
trait
more
frequent
in
males
than
in
females.
Artificially
acquired
passive
immunity
is
the
treatment.
