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Chemotactic Activity

Chemotaxis is the unidirectional migra­tion of cells towards an increasing concentration of a chemical attract­ant. Antigen-antibody complexes which have bound complement have been found to attract phagocytic cells. Thus complement acts as a chemotactic factor. C5a, C3a, and C5b, 6, 7 complex are chemotactic for certain leucocytes. This promotes accumulation of leucocytes at tissue sites where immune reactions are taking place.