Gell
and
Coombs
Chart
of
Classification
of
Hypersensitivity
In the early 1970s, P.G.H. Gell and R.A. Coombs proposed another method
of classification of hypersensitivity. Their classification is as follows: 1. Immediate hypersensitivity.
It
includes
three
types:
(a) Type
I
(anaphylactic
hypersensitivity).
It
involves
IgE,
mast
cells,
basophils
and
mediators
that
induce
muscle
contraction.





