Microbiology Procedure
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Immune Complexes and Serum Sickness

Immune Complexes and Serum Sickness

In some individuals the immune system may recognise foreign serum proteins as antigens and may form antibodies against them in an allergic reaction. When the antibodies interact with the proteins, a series of chemical molecules called immune complexes may form, and with activation of complement, the person may develop a type of disease called serum sickness.

This type of immunity provides substantial and immediate protection to disease, but is only a temporary measure. This goes off after few days. Examples are the serum preparations for chickenpox, hepatitis B etc.

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