Immunoferritin
Labelling
This
technique
is
an
adaptation
of
the
labelling
principle
of
fluorescent
antibody
staining.
In
this
method
of
the
antibody
is
conjugated
to
an
electrondense
molecule,
such
as
ferritin,
and
is
made
visible,
under
the
electron
microscope.
Ferritin
is
an
organic
complex
of
ferric
hydroxide
and
ferric
phosphate
associated
with
apoferritin,
a
protein
of
the
liver
and
spleen
that
serves
as
a
storage
place
of
iron.
Cells
are
incubated
with
ferritin-conjugated
antibody.
Cell
sections
are
then
examined
under
the
election
microscope.
Ferritin
molecules
can
be
observed
on
the
cell
surface
where
antibodies
are
bound.
