Light
Chains
Each
light
chain
consists
of
about
214
amino
acid
residues.
It
is
divided
into
a
variable
region
V
(residues
1
to
198)
and
a
constant
region
C
(residues
109
to
214).
The
variable
and
constant
regions
of
the
light
chains
are
known
as
VL
and
CL,
respectively.
Myeloma
patients
secrete
specific
proteins,
called
Bence
Jones
proteins,
in
their
urine.
These
proteins
have
been
shown
to
be
dimers
of
the
light
chains
of
the
myeloma
antibody.
Over
production
of
light
chains
in
comparison
to
the
heavy
chains
results
in
the
excretion
of
the
former.
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Index >>Immunity >> Light Chains
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