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Severe Combined Immunodeficiency SCID

Severe Combined Immunodeficiency SCID

This is the most dangerous one. as it is accompanied by defects in both humoral and cellular immunity. The B-lymphocyte and T-lymphocyte areas of the lymph nodes are depleted .of lymphocytes, and all immune function is suppressed. The disease develops due to failure in the normal development of both thymus and bursa equivalent.

The longest surviving victim of SCID was boy, David, who lived for 12 years inside a sterile, plastic bubble at the Baylor College of Medicine in Houston. In 1983, he had received a bone narrow transplant from his sister for establishing immune system. But later he died, when was removed from bubble, as victim of blood cancer, the virus brought through transplant.

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