Somatic
Recombination
Theory
According to this theory, a comparatively fewer number of genes (of the order of 100) specify the V region of immunoglobulin molecules. These genes can then undergo intrachromosomal recombination in antibody-producing cells, giving rise to several different amino acid sequences. Thus it has been calculated that recombination among 10 different genes could give rise to different polypeptides.
