Synthetic
Vaccines
/
Third
Generation
Vaccines
Another
form
of
vaccines
are
the
synthetic
vaccines,
or
third
generation
vaccines.
Their
preparation
is
based
on
application
of
recombinant
DNA
technology.
Briefly
the
whole
procedure
involves:
(i)
the
immune
stimulating
antigen
must
be
identified,
(ii)
live
cells
must
be
reengineered
to
produce
the
antigens;
and
(iii)
the
size
of
the
antigens
must
be
increased
to
promote
phagocytosis
and
the
immune
response.
A
vaccine
of
this
type
is
licensed
in
1981.
This
is
vaccine
for
foot
and
mouth
disease.
For
other
vaccines,
work
is
in
progress.
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