Human Protein Synthesis

Human Protein Synthesis

Human Protein Synthesis- Genetic engineering has expanded the industrial applications of microorganisms including production of human proteins. By using recombinant DNA technology, human DNA sequences that code for various proteins have been incorporated into the genomes of bacteria. By growing these recombinant bacteria in fermentors, human proteins could be produced commercially.

Human insulin, for instance, is produced by a recombinant E. coli strain and marketed as humulin. Other strains are used to produce human growth hormone, tumor necrosis factor (TN F), interferon (human recombinant beta interferon-trade name, Betaseron), and inter- leukin-2 (human recombinant interleukin-2, trade name- Prolcukin).

Humulin is used in treatment of diabetes in individuals allergic to insulin harvested from cattle. Human growth factor is used in treatment of dwarfism, and interleukin- 2, interferon and TNF are important components of human immune system

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