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Index >> Industrial Microbiology >> Semisolid or Solid State Mehtods

Semisolid or Solid State Mehtods

Semi Solid OR Solid State Methods - In this the culture medium is impregnated in a carrier such as bagasse, wheat bran, potato pulp, etc. and the organism is allowed to grow on this. This method allows greater surface area for growth. The production of the desirable substance and the recovery is generally easier and satisfactory.

In the development of a fermentation process, the composition of the culture medium plays a major role and will determine to a very great extent the level of end product. For example, a culture medium containing sucrose enables better production of citric acid by A. niger than any other carbohydrate. The pH, temperature of incubation, aeration etc., are all important factors in fermentations and these have to be optimized for each type of fermentation. Emphasis is generally placed on the use of cheap raw materials so that the cost of production is low.

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