Electrogenic
Sodium
Pump
There
is
no
on
to
one
exchange
of
Na+
and
K+.
The
exit
of
Na+
is
not
compensated
by
the
entry
of
K+.
In
the
most
common
sodium
pump
the
movement
of
3Na+
from
the
inside
of
the
cell
to
the
outside
is
exchanged
for
2K+
in
the
opposite
direction.
The enzyme catalyzing the exchange of Na+ and K + is called sodium potassium ATPase.The reaction is driven by the splitting of a molecule of ATP to ADP + Pi.
One
mechanism
proposed
for
the
reaction
is
as
follows.
The
first
step
is
the
binding
of
3Na+
and
ATP
to
the
enzyme.
This
is
followed
by
the
hydrolysis
of
ATP
to
form
the
phosphorylated
enzyme
and
ADP
Index >> Membrane Transport >> Electrogenic Sodium Pump
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