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Index >> Metabolic Regulation >> Regulatory Mechanism in Microorganisms

Regulatory Mechanism in Microorganisms

Regulatory Mechanism in Microorganisms

Mechanism -Enzyme Induction : Negative Control Example - Induction of β-galactosidase
Allosteric Protein - The repressor ( The Product of i-gene )
Effector - Inducer
Physiological Result - Enzymes synthesized only when substrate inducer is presnt in the medium

Mechanism - Catabolite Repression: Positive Control
Example -  Glucose repression of β-galactosidase synthesis
Allosteric Protein - CAP Protein
Effector -  c -AMP
Physiological Result - Allows cells to use most favourable source of carbon,regulates catabolic rate

Mechanism - Enzyme Induction: Positive Control
Example - Induction of enzymes that metabolise arabinose
Allosteric Protein - Repressor activator ( Product of araC gene)
Effector - Inducer Arabinose
Physiological Result - Enzymes synthesized only when the substrate is present in the medium

Mechanism - End-Product Repression
Example - Regulation of Enzymes Necessary for synthesis of Tryptophan

Allosteric Protein - Repressor ( Product of trp R gene)
Effector - Tryptophan
Physiological Result - Regulates synthesis of enzymes of trptophan biosynthetic pathway

Mechanism - End-Product Inhibition
Example - Feedback control of pyrimidine synthesis
Allosteric Protein - Aspartate transcarbamylase
Effector - Cytidine triphosphate
Physiological Result- Regualtes biosynthesis of small molecules ( CTP )

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