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Actinomycetes

Actinomycetes - Majority of them are mycelial. They are Gram positive prokaryotes, a large group of filamentous bacteria which characteristically show branching patterns just like those of fungi, to give rise to a spreading mycelium.

Also, like fungi, they often readily produce spores when grown in culture. They are easily isolated from soil. Most of these, particularly Streptomyces, produce antibiotics, and so are of great value to the pharmaceutical industry. Their main characteristics are:

(1) Mycelial (majority), Gram positive prokaryotes.

(2) Some (euactinomycetes) develop only in mycelial state reproducing by unicellular specialised spores (e.g. Streptomyces, Micromonospora , Actino planes, Strepto sporangium, Thermoactinomyces; in others (proactinomycetes) mycelial development is transitory and often limited, specialised spores not produced and reproduce primarily by fragmentation into short rod-shaped cells

(e.g. Bifidobacterium, Actinomyces, Mycobacterium. Nocardia, Geodermatophilus) ; and the rest are certain Gram-positive, unicellular bacteria which do not form endospores and which are distinguished from the coryneform group by their regular cell shape, and include the lactic acid bacteria (Streptococcus, Leuconostoc, Pediococcus, Lactobacillus) and micrococci (Staphylococcus, Micrococcus, Sarcina).

(3) Cell wall has some peptidoglycan as in nearly all Gram negative prokaryotes. However, a very large number (almost 60) of other peptidoglycan types have been found in these organisms. The chief variations are the nature of the diaminoacid in position 3: the presence, number and nature of additional amino acids which form interpeptide bridges; and the position of the cross link between peptide chains.

 

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