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Meiosis

Meiosis - In sexually reproducing organisms cellular fusion followed by a reduction in the chromosome number is an important feature. The two cells that participate in sexual reproduction are called gametes which fuse to form a zygote. This is followed by a nuclear fusion and the zygote nucleus contains two complete sets of genetic determinants (2N).

In order to maintain the original haploid number in succeeding generations, there must be a stage during which a reduction in the chromosome number occurs. This process which Occurs after the fusion of the gametes is called as meiosis.In brief, meiosis consists of two meiotic divisions. In the prophase of the first meiotic division, the homologous chromo­somes become visible as single strands which then undergo pairing. Later, each chromosome becomes visible as two chromatids and crossing over occurs.

This is followed by metaphase I, in which orientation of paired chromosomes in an equatorial plane and the formation of spindle apparatus takes place. Anaphase I follows, and the homologous centromeres move to the opposite poles of the spindle.

In telophase I which constitutes the end of the first meiotic division the formation of two nuclei occurs. After this, the interphase II follows, during which chromosomes elongate. Centromere division and migration of the homologous chromatids occurs during prophase II and metaphase II, which is followed by anaphase II and the second meiotic division resulting in the formation of four haploid cells.

In many eucaryotic protists of higher ploidy (>1) meiosis occurs after the formation of the zygote and prior to spore formation. In some eucaryotes there may even be a well marked alteration of haploid and diploid generations as in the case of the yeast. In this, the diploid zygote gives rise to a diploid individual which then yields haploid cells only after meiosis. The haploid cell can either multiply as a haploid or fuse with another haploid of the opposite mating type to give again a diploid.

A typical example of the life cycle of  the eucaryotic protist, the yeast Saccharomyces cerevisiae. Although sexual reproduction may be the only method of reproduction in most animals and plants, it is not an obligatory event in the life cycles of many protists. Many protists lack a sexual stage in their life cycle and even in species in which sexuality does exist, sexual reproduction may be infrequent.

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