Microorganism Controlling by Tetracyclines - They are also broad spectrum antibiotics with range of activity similar to chloramphenicol. They include naturally occurring chlortetracycline and oxtetracycline, isolated from species of Streptomyces. They may be taken orally. Though they have side effects problems, they remain the drugs of choice for most rickettsial and chlamydial diseases.
They are used in Gram negative infections as brucellosis, plague, cholera, for primary atypical pneumonia, as substitutes for penicillin in syphilis, anthrax, gonorrhea, and pneumonia; and therapy of some protozoan infections as amoebiasis.
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