In
addition
to
these,
a
number
of
other
antibiotics
inhibit
protein
synthesis.
These
are
tetracyclines,
chloramphenicol,
erythromycin,
lincomycin,
clindamycin
and
Spectinomycin.
Chloramphenicol,
unlike
others
acts
primarily
by
binding
to
the
50s
ribosomal
subunit,
preventing,
he
binding
of
tRNA
molecules
to
both
the
amino
acyl
and
peptidyl
binding
sites
of
the
ribosome.
Erythromycin
also
binds
to
50s
ribosomal
subunit.
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