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Escape of Chimeric Microorganisms

Escape of Chimeric Microorganisms
The possibility exists that microorganisms with recombinant DNA might escape .from the laboratory and be perpetuated and irreversably fixed in living organisms. If the microbial hosts of recombinant DNA inhabit humans, the likelihood of escape from the laboratory to the natural ecological environment is greater than for microorganisms living on soil and or plants.

Use of microorganisms that occupy special ecological niches like hot springs and salt water would pose less hazard in the event of escape.The agencies by which microorganism can escape from the laboratory are laboratory personnel (such as scientists, dishwashers, media preparers. visitors, etc.) laboratory facilities (glassware, drainage) spills and aerosolization.

Laboratory personnel may not be fully conversant with the precautions to be followed in research on pathogenic microorganisms, or may not observe the precautions. Laboratory workers often acquire immunity against microorganism with which they are working and may thus act as carriers.

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