Penicillin
Enrichment
Techniques
Mutation rates can be increased by the use of mutagens like UV -light, ionizing radiations and chemicals like nitrous acid, nucleotide analogues etc. Methods have been developed for isolation of a particular desired type of mutant.
There may be some difficulty in finding a suitable method 10 enrich specifically for the desired mutant and to recognise and isolate it when it may still be only a small proportion of the irradiated population. Direct selection can only be achieved when the mutation gives rise to resistance to a chemical or virus
