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Lactic Acid Fermentations

Lactic Acid Fermentations - This is one of the oldest and simplest fermentations known and is important in the souring of milk. In this fermentation, a NAD linked lactic dehydrogenase reduces pyruvate to lactate quantitatively. Since 2 moles ATP are consumed in the formation of a hexose diphosphate from glucose and 4 moles of ATP are subsequent produced, the net yield is 2 moles of ATP per mole of hexose.

Many lactic bacteria such as Lactobacillus casei, Streptococcus cremoris etc, carry out lactic fermentations in which lactic acid is the only end Product. Some other members of the lactic group carry nut a heterolactic fermentation in which only half of the glucose is converted into lactate. In heterolactics, glucose is fermented through phospho ketolase pathway to lactic acid, ethanol and CO2.

In addition to these two fermentations, a variety of other fermentations have been identified in microorganisms which yield different products. Here, it is not the purpose to describe them in detail but some will be briefly described. In all these fermentations, the glycolytic pathway (glucose pyruvic acid) is common and pyruvate is the key intermediate and the fate of pyruvate in these various fermentations

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