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Index >> Microbial Metabolism >> Pentose Phosphate Cycle

Pentose Phosphate Cycle

Pentose Phosphate Cycle - For a long time it was thought that the EMP was the sole pathway of glucose metabolism in microorganisms but now it has been found that the pentose phosphate cycle (Hexose monophosphate shunt) is of major importance in many microorganisms.

The pathway involves the oxidative decarboxylation of a hexose molecule to a pentose followed by the rearrangement of the carbon skeleton of the pentose produced .The reactions eventually yield CO2 and water with the generation of 30 mole of ATP per mole of hexose of which one mole is utilised. This pathway is therefore energetically one of the most important mechanism by which cells derive energy by complete oxidation of glucose to CO2 and water in addition to providing a variety of intermediates for biosynthetic processes.

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