Microbiology Procedure
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Index >> Microbiology in Biotechnology >> Microbes in Medicine

Microbes in Medicine

Microbes in Medicine- Antibiotic and other chemotherapeutic agents production by a range of microbes is well-known. Recent development in this area has been the use of microbial biotechnology in steroid transformations and biotrans­formation of natural pencillin G to several semi-synthetic penicillns. Penicillin acylase produced by Saccharomyces cerevisiae and Kluyvera citro phila is used in biotransformation of penicillin G to semi-synthetic penicillins.

Microbial transformation of steroids is very important in pharmaceutical industry. Rhizopus nigricans hydroxylates progesterone forming another steroid. Cunninghamella blakesleeana hydroxylates cortexolone to hydro­cortesone.

Details are given in Chapter on "Industrial Microbiology."

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