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Index >>Prokaryotes Microbes >> Mycobacteria

Mycobacteria

Mycobacteria -  Mycobacteria are a group of non motile rods that are defined on the basis of a distinctive staining property: they are relatively Impermeable to various basic dyes, but once stained they retain dyes with tenacity. Specifically, they resist decolorization with. acidified organic solvents, and are, therefore, calIed acid fast. This property, and their relatively slow growth, are attributed to their lipid rich cell wall. Mycobacteria range from widespread innocuous saprophytic inhabitants of soil and water to organisms which are responsible for tuberculosis and leprosy. Tuberculosis is usually confined to internal organs,Where as leprosy largely involves the skin.

The leprosy bacillus, discovered by Hansen in 1879, was the first bacterium shown to be associated with human disease. It is strikingly adapted to man. It has been difficult to transfer to any other host, and it has not been grown on artificial culture media. In contrast, the agents of human tuberculosis, Mycobacterium tuberculosis and the closely related M.bovis  are readily cultivated on simple media, and are pathogenic to various lower animals, especially guinea pigs and mice. Mycobacteria are considered transitional forms between true bacteria (eubacteria) and actinomycetales.

 

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