Weil
Felix
Test -
This
test
is
used
to
identify
the
presence
of
rickettsiae
without
specifying
a
particular
species.
A
sample
of
patients
blood
is
first
obtained,
and
the
clean
serum
is
separated
from
the
red
blood
cells.
A
sample
of
serum
is
mixed
with
the
cells
of
the
bacterium,
Proteus
Ox19.
The
bacteria
will
clump
together
if
the
serum
contains
antibodies
against
the
rickekttsiae,
indicating
that
a
person
has
the
disease
or
once.
had
it.
If
no
clumping
takes
place,
rickettsial
antibodies
are
probably
not
present.
The
Weil
Felix
test
works
because
rickettsiae
possess
antigens,
also
located
in
Proteus
cells
and
therefore,
both
organisms
stimulate
the
immune
system
to
produce
the
same
antibodies





