Microbiology Procedure
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Central Dogma of Protein Synthesis

Central Dogma of Protein Synthesis - Proteins constitute the major part by dry weight of an actively growing cell. They are widely distributed in living matter. All enzymes are proteins. Proteins are built up from about 20 amino acids which constitute the basic building blocks. In proteins the amino acids are linked up by peptide bonds to from long chains called polypeptides.

The sequence of amino acids has a bearing on the properties of a protein, and is characteristic for a particular protein. The basic mechanism of protein synthesis is that DNA makes RNA, which in turn makes protein. The central dogma of protein synthesis is expressed as follows:

  Replication Transcription Translation
DNA ----------------> DNA --------------------> RNA -------------> PROTEIN

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