Microbiology Procedure
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Index >> Ribosomes >> RNA Content of Mitoribosomes

RNA Content of Mitoribosomes

RNA Content of Mitoribosomes - The small subunit of the mitoribosome contains 12­13S rRNA and the large subunit 16-17S rRNA. The RNA content of mitoribosomes is much less than that of cytoribosomes.

They contain only about half the RNA of bacterial ribosomes. Mitoribosomal RNAs have a comparatively low O+C content (30-40%), unlike most ribosomal RNAs. Mitochondrial RNA also generally has less secondary structure, as is shown by its relatively lower content of methylated bases, in comparison to other ribosomal RNAs.

The 5S rRNA of prokaryotic and eukaryotic ribosomes plays an important role in binding aminoacyl- tRNA to the ribosome.

Until recently it was believed that mitoribosomes do not contain 5S rRNA. Some studies, however, suggest that an RNA molecule analogous to 5S rRNA is present in animal systems.

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