Agglutination -
In
this
reaction
antibodies
react
with
antigens
on
the
surface
of
particulate
objects
and
cause
the
objects
to
clump
together,
or
agglutinate.
These
reactions
were
the
earliest
to
be
adapted
to
diagnostic
laboratory.
Widal
test
is
used
for
diagnosis
of
typhoid
fever.
This
test,
developed
by
Georges
Fernand
I.
Widal
(French
physician)
in
1896,
is
now
supplemented
by
more
sophisticated
procedures.
A
polyvalent
serum
(a
serum
containing
a
mixture
of
antibodies)
is
prepared.





