Flocculation -
This
test
combines
the
principles
of
precipitation
and
agglutination.
The antigen
exists
in
a
non
cellular
particulate
form
that
reacts
with
antibodies
to
form
large,
visible
aggregates.
An
example
of
this
test
is
Veneral
Disease
Research
Laboratory
(VDRL)
test
used
for
the
rapid
screening
of
patients
to
detect
syphilis.
The
antigen
is
alcoholic
extract
of
beef
heart
called
cardiolipin.
This
reacts
with
syphilis
antibodies
in
patients'
serum
to
form
aggregates
Index >> Serology >> Flocculation
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