|
Stains For Virus Inclusion Bodies |
|
|
Stains For Virus Inclusion Bodies
Inclusion body is the site at which virus morphogenesis proceeds during the virus infection cycle. Herpesviruses and adenoviruses form inclusions in the nucleus. Herpesviruses form Type-A inclusions, which are characteristically single homogeneous eosinophilic bodies that occupy the central area of the nucleus and are clearly separated from the marginated chromatin.
|
Adenoviruses form Type-B inclusions, which are formed by condensation of basophilic material, including nuclear chromatin, into a single central mass or into multiple discrete bodies. Their detection is of great value in diagnosis of viral infections. Several stains are available for their demonstration. Depending upon the nature e.g. acidophilic or basophilic, they take up and react with staining solution.
|
|
